Novartis' Guidelines*

"between 1.0 mg and .75 mg per pound of body weight"

(between 0.04-0.03 ml of Percorten-v per pound of body weight)

0.04 ml DOCP per lb. (recommended STARTING DOSE per Novartis)

0.03 ml DOCP per lb. (at .75mg/pound of body weight)

There are 100 mgs of DOCP in a 4.0 ml vial of Percorten-v.

The RECOMMENDED STARTING DOSE (per Novartis)

is 1 mg per pound of body weight -or 0.04 ml of DOCP per pound.

One vial of DOCP contains 100 mg, but since the dosage amount depends on the weight of the dog,

a 50 pound dog would start out on 50 mg, a 100 pound dog would start out on 100 mg, etc.

Dosage Calculations: ("Starting" amount, and with -10% adjustment)

Enter current weight HERE: 10.0 lbs.

0.40 ml "recommended starting dosage" per Novartis (1mg/lb)

less: (0.04) adjusted dosage* -10%

0.36 adjusted dosage (@ .9 mg/lb) for 10 lbs of body weight

Enter current weight HERE: 25.0 lbs.

1.00 ml "recommended starting dosage" per Novartis (1mg/lb)

less: (0.10) adjusted dosage* -10%

0.90 adjusted dosage (@ .9 mg/lb) for 25 lbs of body weight

Enter current weight HERE: 50.0 lbs.

2.00 ml "recommended starting dosage" per Novartis (1mg/lb)

less: (0.20) adjusted dosage* -10%

1.80 adjusted dosage (@ .9 mg/lb) for 50 lbs of body weight

Enter current weight HERE: 75.0 lbs.

3.00 ml "recommended starting dosage" per Novartis (1mg/lb)

less: (0.30) adjusted dosage* -10%

2.70 adjusted dosage (@ .9 mg/lb) for 75 lbs of body weight

Enter current weight HERE: 100.0 lbs.

4.00 ml "recommended starting dosage" per Novartis (1mg/lb)

less: (0.40) adjusted dosage* -10%

3.60 adjusted dosage (@ .9 mg/lb) for 100 lbs of body weight

*Novartis' Guidelines*

"Dosage requirements are variable and must be individualized on the basis of

the response of the patient to therapy. Begin treatment with PERCORTEN-V at a

dose of 1.0 mg per pound of body weight every 25 days. In some patients the

dose may be reduced. Serum sodium and potassium levels should be monitored to

assure the animal is properly compensated. Most patients are well controlled

with a dose range of 0.75 to 1.0 mg per pound of body weight, given every 21 to 30 days.

The well-controlled patient will have normal electrolytes at 14 days after

administration or may exhibit slight hyponatremia and hyperkalemia. This

needs no additional therapy as long as the patient is active and eating

normally. Watch closely for depression, lethargy, vomiting or diarrhea which

indicate a probable glucocorticoid deficiency."

146.0 lbs. (Catherine's optimum weight)

5.84 ml (at 1.0 mg/lb)

(0.88) adjusted dosage* -15%

4.96 (Catherine's optimum dosage: 5.0 ml/28 days)